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Aging-related chromatin defects via loss of the NURD complex
Physiological and premature aging are characterized by multiple defects in chromatin structure and accumulation of persistent DNA damage. Here we identify the NURD remodeling complex as a key modulator of these aging-associated chromatin defects. We demonstrate loss of several NURD components during...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779731/ https://ncbi.nlm.nih.gov/pubmed/19734887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1971 |
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