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Aging-related chromatin defects via loss of the NURD complex
Physiological and premature aging are characterized by multiple defects in chromatin structure and accumulation of persistent DNA damage. Here we identify the NURD remodeling complex as a key modulator of these aging-associated chromatin defects. We demonstrate loss of several NURD components during...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779731/ https://ncbi.nlm.nih.gov/pubmed/19734887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1971 |
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