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Protein sequestration at the nuclear periphery as a potential regulatory mechanism in premature aging

Despite the extensive description of numerous molecular changes associated with aging, insights into the driver mechanisms of this fundamental biological process are limited. Based on observations in the premature aging syndrome Hutchinson–Gilford progeria, we explore the possibility that protein re...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Main Authors: Serebryannyy, Leonid, Misteli, Tom
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5748986/
https://ncbi.nlm.nih.gov/pubmed/29051264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706061
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