DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor

Transplantation of DA neurons is actively pursued as a restorative therapy in Parkinson’s disease (PD). Pioneering clinical trials using transplants of fetal DA neuroblasts have given promising results, although a number of patients have developed graft-induced dyskinesias (GIDs), and the mechanism...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Aldrin-Kirk, Patrick, Heuer, Andreas, Wang, Gang, Mattsson, Bengt, Lundblad, Martin, Parmar, Malin, Björklund, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893163/
https://ncbi.nlm.nih.gov/pubmed/27161524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.04.017
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados