Novel AAV-Based Rat Model of Forebrain Synucleinopathy Shows Extensive Pathologies and Progressive Loss of Cholinergic Interneurons

Por Aldrin-Kirk, Patrick, Davidsson, Marcus, Holmqvist, Staffan, Li, Jia-Yi, Björklund, Tomas
Publicado em 2014

DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor

Por Aldrin-Kirk, Patrick, Heuer, Andreas, Wang, Gang, Mattsson, Bengt, Lundblad, Martin, Parmar, Malin, Björklund, Tomas
Publicado no Neuron (2016)

A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism

Por Davidsson, Marcus, Wang, Gang, Aldrin-Kirk, Patrick, Cardoso, Tiago, Nolbrant, Sara, Hartnor, Morgan, Mudannayake, Janitha, Parmar, Malin, Björklund, Tomas
Publicado no Proc Natl Acad Sci U S A (2019)

Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing

Por Davidsson, Marcus, Díaz-Fernández, Paula, Torroba, Marcos, Schwich, Oliver D., Aldrin-Kirk, Patrick, Quintino, Luis, Heuer, Andreas, Wang, Gang, Lundberg, Cecilia, Björklund, Tomas
Publicado no RNA (2018)

Modelling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

Por Rifes, Pedro, Isaksson, Marc, Rathore, Gaurav Singh, Aldrin-Kirk, Patrick, Møller, Oliver Knights, Barzaghi, Guido, Lee, Julie, Egerod, Kristoffer Lihme, Rausch, Dylan Matthew, Parmar, Malin, Pers, Tune H., Laurell, Thomas, Kirkeby, Agnete
Publicado no Nat Biotechnol (2020)

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency

Por Tordo, Julie, O’Leary, Claire, Antunes, André S L M, Palomar, Nuria, Aldrin-Kirk, Patrick, Basche, Mark, Bennett, Antonette, D’Souza, Zelpha, Gleitz, Hélène, Godwin, Annie, Holley, Rebecca J, Parker, Helen, Liao, Ai Yin, Rouse, Paul, Youshani, Amir Saam, Dridi, Larbi, Martins, Carla, Levade, Thierry, Stacey, Kevin B, Davis, Daniel M, Dyer, Adam, Clément, Nathalie, Björklund, Tomas, Ali, Robin R, Agbandje-McKenna, Mavis, Rahim, Ahad A, Pshezhetsky, Alexey, Waddington, Simon N, Linden, R Michael, Bigger, Brian W, Henckaerts, Els
Publicado no Brain (2018)