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BCFtools/RoH: a hidden Markov model approach for detecting autozygosity from next-generation sequencing data
Summary: Runs of homozygosity (RoHs) are genomic stretches of a diploid genome that show identical alleles on both chromosomes. Longer RoHs are unlikely to have arisen by chance but are likely to denote autozygosity, whereby both copies of the genome descend from the same recent ancestor. Early tool...
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| Izdano u: | Bioinformatics |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4892413/ https://ncbi.nlm.nih.gov/pubmed/26826718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw044 |
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