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pHMM-tree: phylogeny of profile hidden Markov models

Protein families are often represented by profile hidden Markov models (pHMMs). Homology between two distant protein families can be determined by comparing the pHMMs. Here we explored the idea of building a phylogeny of protein families using the distance matrix of their pHMMs. We developed a new s...

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Dettagli Bibliografici
Pubblicato in:Bioinformatics
Autori principali: Huo, Luyang, Zhang, Han, Huo, Xueting, Yang, Yasong, Li, Xueqiong, Yin, Yanbin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860389/
https://ncbi.nlm.nih.gov/pubmed/28062446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw779
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