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pHMM-tree: phylogeny of profile hidden Markov models

Protein families are often represented by profile hidden Markov models (pHMMs). Homology between two distant protein families can be determined by comparing the pHMMs. Here we explored the idea of building a phylogeny of protein families using the distance matrix of their pHMMs. We developed a new s...

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Detalles Bibliográficos
Publicado en:Bioinformatics
Main Authors: Huo, Luyang, Zhang, Han, Huo, Xueting, Yang, Yasong, Li, Xueqiong, Yin, Yanbin
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860389/
https://ncbi.nlm.nih.gov/pubmed/28062446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw779
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