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BCFtools/RoH: a hidden Markov model approach for detecting autozygosity from next-generation sequencing data

Summary: Runs of homozygosity (RoHs) are genomic stretches of a diploid genome that show identical alleles on both chromosomes. Longer RoHs are unlikely to have arisen by chance but are likely to denote autozygosity, whereby both copies of the genome descend from the same recent ancestor. Early tool...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioinformatics
Egile Nagusiak: Narasimhan, Vagheesh, Danecek, Petr, Scally, Aylwyn, Xue, Yali, Tyler-Smith, Chris, Durbin, Richard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892413/
https://ncbi.nlm.nih.gov/pubmed/26826718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw044
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