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Short-range template switching in great ape genomes explored using pair hidden Markov models

Many complex genomic rearrangements arise through template switch errors, which occur in DNA replication when there is a transient polymerase switch to an alternate template nearby in three-dimensional space. While typically investigated at kilobase-to-megabase scales, the genomic and evolutionary c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Genet
Egile Nagusiak: Walker, Conor R., Scally, Aylwyn, De Maio, Nicola, Goldman, Nick
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954356/
https://ncbi.nlm.nih.gov/pubmed/33651813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009221
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