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De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET

Endogenous retroviruses (ERVs) undergo de novo DNA methylation during the first few days of mammalian embryogenesis, although the factors that control the targeting of this process are largely unknown. We asked if KAP1 (KRAB-associated protein 1) is involved in this mechanism because of its previous...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Rowe, Helen M., Friedli, Marc, Offner, Sandra, Verp, Sonia, Mesnard, Daniel, Marquis, Julien, Aktas, Tugce, Trono, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892343/
https://ncbi.nlm.nih.gov/pubmed/23293284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087585
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