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De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET

Endogenous retroviruses (ERVs) undergo de novo DNA methylation during the first few days of mammalian embryogenesis, although the factors that control the targeting of this process are largely unknown. We asked if KAP1 (KRAB-associated protein 1) is involved in this mechanism because of its previous...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Development
Prif Awduron: Rowe, Helen M., Friedli, Marc, Offner, Sandra, Verp, Sonia, Mesnard, Daniel, Marquis, Julien, Aktas, Tugce, Trono, Didier
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892343/
https://ncbi.nlm.nih.gov/pubmed/23293284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087585
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