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De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET

Endogenous retroviruses (ERVs) undergo de novo DNA methylation during the first few days of mammalian embryogenesis, although the factors that control the targeting of this process are largely unknown. We asked if KAP1 (KRAB-associated protein 1) is involved in this mechanism because of its previous...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Rowe, Helen M., Friedli, Marc, Offner, Sandra, Verp, Sonia, Mesnard, Daniel, Marquis, Julien, Aktas, Tugce, Trono, Didier
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892343/
https://ncbi.nlm.nih.gov/pubmed/23293284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087585
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