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Mechanisms of resistance to FLT3 inhibitors
The success of the small molecule tyrosine kinase receptor inhibitor (TKI) imatinib mesylate (Gleevec) in the treatment of chronic myeloid leukemia (CML) constitutes an eminent paradigm shift advocating the rational design of cancer therapeutics specifically targeting the transformation events that...
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Publicado no: | Drug Resist Updat |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891941/ https://ncbi.nlm.nih.gov/pubmed/19162530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drup.2008.12.001 |
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