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Mechanisms of resistance to FLT3 inhibitors and the role of the bone marrow microenvironment
The presence of FLT3 mutations in AML carries a particularly poor prognosis making the development of FLT3 inhibitors an imperative goal for these patients. The last decade has seen an abundance of clinical trials using these drugs alone or in combination with chemotherapy. This culminated with the...
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| Publicado no: | Hematol Oncol Clin North Am |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512588/ https://ncbi.nlm.nih.gov/pubmed/28673395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2017.04.005 |
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