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FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo
We examined in vivo FLT3 inhibition in acute myeloid leukemia patients treated with chemotherapy followed by the FLT3 inhibitor lestaurtinib, comparing newly diagnosed acute myeloid leukemia patients with relapsed patients. Because we noted that in vivo FLT3 inhibition by lestaurtinib was less effec...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069670/ https://ncbi.nlm.nih.gov/pubmed/21263155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-266742 |
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