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FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo
We examined in vivo FLT3 inhibition in acute myeloid leukemia patients treated with chemotherapy followed by the FLT3 inhibitor lestaurtinib, comparing newly diagnosed acute myeloid leukemia patients with relapsed patients. Because we noted that in vivo FLT3 inhibition by lestaurtinib was less effec...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069670/ https://ncbi.nlm.nih.gov/pubmed/21263155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-266742 |
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