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Excessive Activation of TGFβ by Spinal Instability Causes Vertebral Endplate Sclerosis

Narrowed intervertebral disc (IVD) space is a characteristic of IVD degeneration. EP sclerosis is associated with IVD, however the pathogenesis of EP hypertrophy is poorly understood. Here, we employed two spine instability mouse models to investigate temporal and spatial EP changes associated with...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Bian, Qin, Jain, Amit, Xu, Xin, Kebaish, Khaled, Crane, Janet L., Zhang, Zhendong, Wan, Mei, Ma, Lei, Riley, Lee H., Sponseller, Paul D., Guo, X. Edward, Lu, Willian Weijia, Wang, Yongjun, Cao, Xu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891769/
https://ncbi.nlm.nih.gov/pubmed/27256073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27093
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