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Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate

In this study the detailed characteristic of the anti-cancer agent 3-bromopyruvate (3-BP) activity in the yeast Saccharomyces cerevisiae model is described, with the emphasis on its influence on energetic metabolism of the cell. It shows that 3-BP toxicity in yeast is strain-dependent and influenced...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Lis, Paweł, Jurkiewicz, Paweł, Cal-Bąkowska, Magdalena, Ko, Young H., Pedersen, Peter L., Goffeau, Andre, Ułaszewski, Stanisław
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891110/
https://ncbi.nlm.nih.gov/pubmed/26862728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7174
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