The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate

This review summarizes the current state of knowledge about the metabolism of cancer cells, especially with respect to the “Warburg” and “Crabtree” effects. This work also summarizes two key discoveries, one of which relates to hexokinase-2 (HK2), a major player in both the “Warburg effect” and canc...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Lis, Paweł, Dyląg, Mariusz, Niedźwiecka, Katarzyna, Ko, Young H., Pedersen, Peter L., Goffeau, Andre, Ułaszewski, Stanisław
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2016
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273842/
https://ncbi.nlm.nih.gov/pubmed/27983708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21121730
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