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Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma

In different fungal and algal species, the intracellular concentration of reduced glutathione (GSH) correlates closely with their susceptibility to killing by the small molecule alkylating agent 3-bromopyruvate (3BP). Additionally, in the case of Cryptococcus neoformans cells 3BP exhibits a synergis...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Niedźwiecka, Katarzyna, Dyląg, Mariusz, Augustyniak, Daria, Majkowska-Skrobek, Grażyna, Cal-Bąkowska, Magdalena, Ko, Young H., Pedersen, Peter L., Goffeau, Andre, Ułaszewski, Stanisław
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323179/
https://ncbi.nlm.nih.gov/pubmed/27582536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11592
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