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Transport of 3-bromopyruvate across the human erythrocyte membrane

3-Bromopyruvic acid (3-BP) is a promising anticancer compound because it is a strong inhibitor of glycolytic enzymes, especially glyceraldehyde 3-phosphate dehydrogenase. The Warburg effect means that malignant cells are much more dependent on glycolysis than normal cells. Potential complications of...

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Détails bibliographiques
Publié dans:Cell Mol Biol Lett
Auteurs principaux: Sadowska-Bartosz, Izabela, Soszyński, Mirosław, Ułaszewski, Stanisław, Ko, Young, Bartosz, Grzegorz
Format: Artigo
Langue:Inglês
Publié: Versita 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275894/
https://ncbi.nlm.nih.gov/pubmed/24715475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/s11658-014-0189-1
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