Guanylate binding protein-1 mediates EGFRvIII and promotes glioblastoma growth in vivo but not in vitro

Glioblastoma multiforme (GBM) is the most common and deadly primary brain tumor in adults. Epidermal growth factor receptor (EGFR) is frequently amplified and mutated in GBM. We previously reported that Guanylate binding protein-1 (GBP1) is a novel transcriptional target gene of EGFR and plays a rol...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Lan, Qing, Wang, Aidong, Cheng, Yanwei, Mukasa, Akitaki, Ma, Jiawei, Hong, Lei, Yu, Shuye, Sun, Lili, Huang, Qiang, Purow, Benjamin, Li, Ming
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891076/
https://ncbi.nlm.nih.gov/pubmed/26848767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7109
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