Guanylate binding protein-1 mediates EGFRvIII and promotes glioblastoma growth in vivo but not in vitro

Glioblastoma multiforme (GBM) is the most common and deadly primary brain tumor in adults. Epidermal growth factor receptor (EGFR) is frequently amplified and mutated in GBM. We previously reported that Guanylate binding protein-1 (GBP1) is a novel transcriptional target gene of EGFR and plays a rol...

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Pubblicato in:Oncotarget
Autori principali: Lan, Qing, Wang, Aidong, Cheng, Yanwei, Mukasa, Akitaki, Ma, Jiawei, Hong, Lei, Yu, Shuye, Sun, Lili, Huang, Qiang, Purow, Benjamin, Li, Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891076/
https://ncbi.nlm.nih.gov/pubmed/26848767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7109
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