Guanylate binding protein-1 mediates EGFRvIII and promotes glioblastoma growth in vivo but not in vitro

Glioblastoma multiforme (GBM) is the most common and deadly primary brain tumor in adults. Epidermal growth factor receptor (EGFR) is frequently amplified and mutated in GBM. We previously reported that Guanylate binding protein-1 (GBP1) is a novel transcriptional target gene of EGFR and plays a rol...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Lan, Qing, Wang, Aidong, Cheng, Yanwei, Mukasa, Akitaki, Ma, Jiawei, Hong, Lei, Yu, Shuye, Sun, Lili, Huang, Qiang, Purow, Benjamin, Li, Ming
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891076/
https://ncbi.nlm.nih.gov/pubmed/26848767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7109
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