Guanylate binding protein-1 mediates EGFRvIII and promotes glioblastoma growth in vivo but not in vitro

Glioblastoma multiforme (GBM) is the most common and deadly primary brain tumor in adults. Epidermal growth factor receptor (EGFR) is frequently amplified and mutated in GBM. We previously reported that Guanylate binding protein-1 (GBP1) is a novel transcriptional target gene of EGFR and plays a rol...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Lan, Qing, Wang, Aidong, Cheng, Yanwei, Mukasa, Akitaki, Ma, Jiawei, Hong, Lei, Yu, Shuye, Sun, Lili, Huang, Qiang, Purow, Benjamin, Li, Ming
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891076/
https://ncbi.nlm.nih.gov/pubmed/26848767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7109
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