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GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells

Growth differentiation factor 15 (GDF15) is an emerging biomarker of cardiovascular risk and disease. Microarray analyses revealed that GDF15 levels were increased during cellular senescence induced by ionizing radiation (IR) in human aortic endothelial cells (HAECs). However, the role of GDF15 in H...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, Hyejin, Kim, Chun-Ho, Jeong, Jae-Hoon, Park, Myungjin, Kim, Kwang Seok
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891072/
https://ncbi.nlm.nih.gov/pubmed/26909594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7457
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