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GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells

Growth differentiation factor 15 (GDF15) is an emerging biomarker of cardiovascular risk and disease. Microarray analyses revealed that GDF15 levels were increased during cellular senescence induced by ionizing radiation (IR) in human aortic endothelial cells (HAECs). However, the role of GDF15 in H...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Park, Hyejin, Kim, Chun-Ho, Jeong, Jae-Hoon, Park, Myungjin, Kim, Kwang Seok
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891072/
https://ncbi.nlm.nih.gov/pubmed/26909594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7457
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