c-Maf regulates pluripotency genes, proliferation/self-renewal, and lineage commitment in ROS-mediated senescence of human mesenchymal stem cells

Mesenchymal stem cells (MSCs) are therapeutically relevant multilineage and immunomodulatory progenitors. Ex vivo expansion of these rare cells is necessary for clinical application and can result in detrimental senescent effects, with mechanisms still largely unknown. We found that vigorous ex vivo...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Chen, Pei-Min, Lin, Chia-Hua, Li, Nan-Ting, Wu, Yao-Ming, Lin, Ming-Tsan, Hung, Shih-Chieh, Yen, Men-Luh
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper: Gerotarget (Focus on Aging)
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742114/
https://ncbi.nlm.nih.gov/pubmed/26496036
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires