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CRP Stimulates GDF15 Expression in Endothelial Cells through p53

Growth differentiation factor 15 (GDF15) is a multifunctional, secreted protein that is a direct target gene of p53. GDF15 is a prospective biomarker of cardiovascular disease (CVD). C-reactive protein (CRP), like GDF15, is implicated in inflammation and an independent biomarker of CVD. However, the...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Kim, Yoonseo, Noren Hooten, Nicole, Evans, Michele K.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008756/
https://ncbi.nlm.nih.gov/pubmed/29967567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8278039
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