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Tristetraprolin suppresses the EMT through the down-regulation of Twist1 and Snail1 in cancer cells
Inhibition of epithelial-mesenchymal transition (EMT)-inducing transcription factors Twist and Snail prevents tumor metastasis but enhances metastatic growth. Here, we report an unexpected role of a tumor suppressor tristetraprolin (TTP) in inhibiting Twist and Snail without enhancing cellular proli...
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| Опубликовано в: : | Oncotarget |
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| Главные авторы: | , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4891015/ https://ncbi.nlm.nih.gov/pubmed/26840564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7094 |
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