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AUF1 promotes stemness in human mammary epithelial cells through stabilization of the EMT transcription factors TWIST1 and SNAIL1

The AU-rich element RNA-binding protein 1 (AUF1) is an RNA-binding protein, which can both stabilize and destabilize the transcripts of several cancer-related genes. Since epithelial-to-mesenchymal transition (EMT) and the acquisition of cancer stem cell traits are important for cancer onset and pro...

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Bibliografiske detaljer
Udgivet i:Oncogenesis
Main Authors: AlAhmari, Manar M., Al-Khalaf, Huda H., Al-Mohanna, Falah H., Ghebeh, Hazem, Aboussekhra, Abdelilah
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406652/
https://ncbi.nlm.nih.gov/pubmed/32759946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00255-1
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