High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria

[Image: see text] In order to identify the most attractive starting points for drugs that can be used to prevent malaria, a diverse chemical space comprising tens of thousands to millions of small molecules may need to be examined. Achieving this throughput necessitates the development of efficient...

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Publicat a:ACS Infect Dis
Autors principals: Swann, Justine, Corey, Victoria, Scherer, Christina A., Kato, Nobutaka, Comer, Eamon, Maetani, Micah, Antonova-Koch, Yevgeniya, Reimer, Christin, Gagaring, Kerstin, Ibanez, Maureen, Plouffe, David, Zeeman, Anne-Marie, Kocken, Clemens H. M., McNamara, Case W., Schreiber, Stuart L., Campo, Brice, Winzeler, Elizabeth A., Meister, Stephan
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2016
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890880/
https://ncbi.nlm.nih.gov/pubmed/27275010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.5b00143
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