Cyclical DNA Methylation and Histone Changes Are Induced by LPS to Activate COX-2 in Human Intestinal Epithelial Cells

Bacterial lipopolysaccharide (LPS) induces release of inflammatory mediators both in immune and epithelial cells. We investigated whether changes of epigenetic marks, including selected histone modification and DNA methylation, may drive or accompany the activation of COX-2 gene in HT-29 human intes...

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Publicado en:PLoS One
Autores principales: Angrisano, Tiziana, Pero, Raffaela, Brancaccio, Mariarita, Coretti, Lorena, Florio, Ermanno, Pezone, Antonio, Calabrò, Viola, Falco, Geppino, Keller, Simona, Lembo, Francesca, Avvedimento, Vittorio Enrico, Chiariotti, Lorenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890762/
https://ncbi.nlm.nih.gov/pubmed/27253528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156671
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