TACC3 mediates the association of MBD2 with histone acetyltransferases and relieves transcriptional repression of methylated promoters

We have recently reported that a novel MBD2 interactor (MBDin) has the capacity to reactivate transcription from MBD2-repressed methylated promoters even in the absence of demethylation events. Here we show that another unrelated protein, TACC3, displays a similar activity on methylated genes. In ad...

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Autors principals: Angrisano, Tiziana, Lembo, Francesca, Pero, Raffaela, Natale, Francesco, Fusco, Alfredo, Avvedimento, Vittorio E., Bruni, Carmelo B., Chiariotti, Lorenzo
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1331987/
https://ncbi.nlm.nih.gov/pubmed/16410616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj400
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