Cyclical DNA Methylation and Histone Changes Are Induced by LPS to Activate COX-2 in Human Intestinal Epithelial Cells

Bacterial lipopolysaccharide (LPS) induces release of inflammatory mediators both in immune and epithelial cells. We investigated whether changes of epigenetic marks, including selected histone modification and DNA methylation, may drive or accompany the activation of COX-2 gene in HT-29 human intes...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Angrisano, Tiziana, Pero, Raffaela, Brancaccio, Mariarita, Coretti, Lorena, Florio, Ermanno, Pezone, Antonio, Calabrò, Viola, Falco, Geppino, Keller, Simona, Lembo, Francesca, Avvedimento, Vittorio Enrico, Chiariotti, Lorenzo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890762/
https://ncbi.nlm.nih.gov/pubmed/27253528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156671
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