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MBDin, a Novel MBD2-Interacting Protein, Relieves MBD2 Repression Potential and Reactivates Transcription from Methylated Promoters

We have identified a human gene encoding a novel MBD2-interacting protein (MBDin) that contains an N-terminal GTP-binding site, a putative nuclear export signal (NES), and a C-terminal acidic region. MBDin cDNA was isolated through a two-hybrid interaction screening using the methyl-CpG-binding prot...

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Udgivet i:Mol Cell Biol
Principais autores: Lembo, Francesca, Pero, Raffaela, Angrisano, Tiziana, Vitiello, Carmen, Iuliano, Rodolfo, Bruni, Carmelo B., Chiariotti, Lorenzo
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151705/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.5.1656-1665.2003
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