MBDin, a Novel MBD2-Interacting Protein, Relieves MBD2 Repression Potential and Reactivates Transcription from Methylated Promoters

We have identified a human gene encoding a novel MBD2-interacting protein (MBDin) that contains an N-terminal GTP-binding site, a putative nuclear export signal (NES), and a C-terminal acidic region. MBDin cDNA was isolated through a two-hybrid interaction screening using the methyl-CpG-binding prot...

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Autors principals: Lembo, Francesca, Pero, Raffaela, Angrisano, Tiziana, Vitiello, Carmen, Iuliano, Rodolfo, Bruni, Carmelo B., Chiariotti, Lorenzo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Transcriptional Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC151705/
https://ncbi.nlm.nih.gov/pubmed/12588985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.5.1656-1665.2003
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