Dynamic Nuclear Polarization Enhanced MAS NMR for Structural Analysis of HIV-1 Protein Assemblies

Mature infectious HIV-1 virions contain conical capsids comprised of CA protein, generated by the proteolytic cleavage cascade of the Gag polyprotein, termed maturation. The mechanism of capsid core formation through the maturation process remains poorly understood. We present DNP-enhanced MAS NMR s...

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Gepubliceerd in:J Phys Chem B
Hoofdauteurs: Gupta, Rupal, Lu, Manman, Hou, Guangjin, Caporini, Marc A., Rosay, Melanie, Maas, Werner, Struppe, Jochem, Suiter, Christopher, Ahn, Jinwoo, Byeon, In-Ja L., Franks, W. Trent, Orwick-Rydmark, Marcella, Bertarello, Andrea, Oschkinat, Hartmut, Lesage, Anne, Pintacuda, Guido, Gronenborn, Angela M., Polenova, Tatyana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890707/
https://ncbi.nlm.nih.gov/pubmed/26709853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b12134
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