Dynamic Nuclear Polarization Enhanced MAS NMR for Structural Analysis of HIV-1 Protein Assemblies

Mature infectious HIV-1 virions contain conical capsids comprised of CA protein, generated by the proteolytic cleavage cascade of the Gag polyprotein, termed maturation. The mechanism of capsid core formation through the maturation process remains poorly understood. We present DNP-enhanced MAS NMR s...

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Udgivet i:J Phys Chem B
Main Authors: Gupta, Rupal, Lu, Manman, Hou, Guangjin, Caporini, Marc A., Rosay, Melanie, Maas, Werner, Struppe, Jochem, Suiter, Christopher, Ahn, Jinwoo, Byeon, In-Ja L., Franks, W. Trent, Orwick-Rydmark, Marcella, Bertarello, Andrea, Oschkinat, Hartmut, Lesage, Anne, Pintacuda, Guido, Gronenborn, Angela M., Polenova, Tatyana
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890707/
https://ncbi.nlm.nih.gov/pubmed/26709853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b12134
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