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The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence
Decreased Na(+), K(+)-ATPase (NKA) activity causes energy deficiency, which is commonly observed in neurodegenerative diseases. The NKA is constituted of three subunits: α, β, and γ, with four distinct isoforms of the catalytic α subunit (α(1−4)). Genetic mutations in the ATP1A2 gene and ATP1A3 gene...
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| Publicado no: | Front Physiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4890531/ https://ncbi.nlm.nih.gov/pubmed/27313535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00195 |
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