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The co-chaperone Cdc37 regulates the rabies virus phosphoprotein stability by targeting to Hsp90AA1 machinery

Cdc37, as a kinase-specific co-chaperone of the chaperone Hsp90AA1 (Hsp90), actively aids with the maturation, stabilization and activation of the cellular or viral kinase/kinase-like targets. Phosphoprotein (P) of rabies virus (RABV) is a multifunctional, non-kinase protein involved in interferon a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xu, Yunbin, Liu, Fei, Liu, Juan, Wang, Dandan, Yan, Yan, Ji, Senlin, Zan, Jie, Zhou, Jiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890047/
https://ncbi.nlm.nih.gov/pubmed/27251758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27123
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