Immuno-targeting the multifunctional CD38 using nanobody

CD38, as a cell surface antigen is highly expressed in several hematologic malignancies including multiple myeloma (MM) and has been proven to be a good target for immunotherapy of the disease. CD38 is also a signaling enzyme responsible for the metabolism of two novel calcium messenger molecules. T...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Li, Ting, Qi, Shali, Unger, Mandy, Hou, Yun Nan, Deng, Qi Wen, Liu, Jun, Lam, Connie M. C., Wang, Xian Wang, Xin, Du, Zhang, Peng, Koch-Nolte, Friedrich, Hao, Quan, Zhang, Hongmin, Lee, Hon Cheung, Zhao, Yong Juan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890012/
https://ncbi.nlm.nih.gov/pubmed/27251573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27055
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