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SMASH, a fragmentation and sequencing method for genomic copy number analysis

Copy number variants (CNVs) underlie a significant amount of genetic diversity and disease. CNVs can be detected by a number of means, including chromosomal microarray analysis (CMA) and whole-genome sequencing (WGS), but these approaches suffer from either limited resolution (CMA) or are highly exp...

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Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Wang, Zihua, Andrews, Peter, Kendall, Jude, Ma, Beicong, Hakker, Inessa, Rodgers, Linda, Ronemus, Michael, Wigler, Michael, Levy, Dan
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889966/
https://ncbi.nlm.nih.gov/pubmed/27197213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.201491.115
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