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Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast

Understanding telomere length maintenance mechanisms is central in cancer biology as their dysregulation is one of the hallmarks for immortalization of cancer cells. Important for this well-balanced control is the transcriptional regulation of the telomerase genes. We integrated Mixed Integer Linear...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Poos, Alexandra M., Maicher, André, Dieckmann, Anna K., Oswald, Marcus, Eils, Roland, Kupiec, Martin, Luke, Brian, König, Rainer
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889924/
https://ncbi.nlm.nih.gov/pubmed/26908654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw111
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