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Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast

Understanding telomere length maintenance mechanisms is central in cancer biology as their dysregulation is one of the hallmarks for immortalization of cancer cells. Important for this well-balanced control is the transcriptional regulation of the telomerase genes. We integrated Mixed Integer Linear...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Poos, Alexandra M., Maicher, André, Dieckmann, Anna K., Oswald, Marcus, Eils, Roland, Kupiec, Martin, Luke, Brian, König, Rainer
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889924/
https://ncbi.nlm.nih.gov/pubmed/26908654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw111
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