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Learning Oncogenetic Networks by Reducing to Mixed Integer Linear Programming

Cancer can be a result of accumulation of different types of genetic mutations such as copy number aberrations. The data from tumors are cross-sectional and do not contain the temporal order of the genetic events. Finding the order in which the genetic events have occurred and progression pathways a...

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Autori principali: Shahrabi Farahani, Hossein, Lagergren, Jens
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3683041/
https://ncbi.nlm.nih.gov/pubmed/23799047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065773
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