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A mixed-integer linear programming approach to the reduction of genome-scale metabolic networks

BACKGROUND: Constraint-based analysis has become a widely used method to study metabolic networks. While some of the associated algorithms can be applied to genome-scale network reconstructions with several thousands of reactions, others are limited to small or medium-sized models. In 2015, Erdrich...

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Publicat a:BMC Bioinformatics
Autors principals: Röhl, Annika, Bockmayr, Alexander
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210269/
https://ncbi.nlm.nih.gov/pubmed/28049424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1412-z
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