An integer linear programming approach for finding deregulated subgraphs in regulatory networks

Deregulation of cell signaling pathways plays a crucial role in the development of tumors. The identification of such pathways requires effective analysis tools that facilitate the interpretation of expression differences. Here, we present a novel and highly efficient method for identifying deregula...

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Autors principals: Backes, Christina, Rurainski, Alexander, Klau, Gunnar W., Müller, Oliver, Stöckel, Daniel, Gerasch, Andreas, Küntzer, Jan, Maisel, Daniela, Ludwig, Nicole, Hein, Matthias, Keller, Andreas, Burtscher, Helmut, Kaufmann, Michael, Meese, Eckart, Lenhof, Hans-Peter
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315310/
https://ncbi.nlm.nih.gov/pubmed/22210863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1227
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