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Machine learning based analyses on metabolic networks supports high-throughput knockout screens
BACKGROUND: Computational identification of new drug targets is a major goal of pharmaceutical bioinformatics. RESULTS: This paper presents a machine learning strategy to study and validate essential enzymes of a metabolic network. Each single enzyme was characterized by its local network topology,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2526078/ https://ncbi.nlm.nih.gov/pubmed/18652654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-2-67 |
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