A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes

The transcriptional shift from repression to activation of target genes is crucial for the fidelity of Notch responses through incompletely understood mechanisms that likely involve chromatin-based control. To activate silenced genes, repressive chromatin marks are removed and active marks must be a...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Oswald, Franz, Rodriguez, Patrick, Giaimo, Benedetto Daniele, Antonello, Zeus A., Mira, Laura, Mittler, Gerhard, Thiel, Verena N., Collins, Kelly J., Tabaja, Nassif, Cizelsky, Wiebke, Rothe, Melanie, Kühl, Susanne J., Kühl, Michael, Ferrante, Francesca, Hein, Kerstin, Kovall, Rhett A., Dominguez, Maria, Borggrefe, Tilman
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889922/
https://ncbi.nlm.nih.gov/pubmed/26912830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw105
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