A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes

The transcriptional shift from repression to activation of target genes is crucial for the fidelity of Notch responses through incompletely understood mechanisms that likely involve chromatin-based control. To activate silenced genes, repressive chromatin marks are removed and active marks must be a...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Oswald, Franz, Rodriguez, Patrick, Giaimo, Benedetto Daniele, Antonello, Zeus A., Mira, Laura, Mittler, Gerhard, Thiel, Verena N., Collins, Kelly J., Tabaja, Nassif, Cizelsky, Wiebke, Rothe, Melanie, Kühl, Susanne J., Kühl, Michael, Ferrante, Francesca, Hein, Kerstin, Kovall, Rhett A., Dominguez, Maria, Borggrefe, Tilman
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889922/
https://ncbi.nlm.nih.gov/pubmed/26912830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw105
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