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Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes

The Notch pathway is a cell-to-cell signaling mechanism that is essential for tissue development and maintenance, and aberrant Notch signaling has been implicated in various cancers, congenital defects, and cardiovascular diseases. Notch signaling activates the expression of target genes, which are...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Tabaja, Nassif, Yuan, Zhenyu, Oswald, Franz, Kovall, Rhett A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481562/
https://ncbi.nlm.nih.gov/pubmed/28487372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.791707
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