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RBP-Jκ/SHARP Recruits CtIP/CtBP Corepressors To Silence Notch Target Genes
Notch is a transmembrane receptor that determines cell fates and pattern formation in all animal species. After ligand binding, proteolytic cleavage steps occur and the intracellular part of Notch translocates to the nucleus, where it targets the DNA-binding protein RBP-Jκ/CBF1. In the absence of No...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1291242/ https://ncbi.nlm.nih.gov/pubmed/16287852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10379-10390.2005 |
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