RBP-Jκ/SHARP Recruits CtIP/CtBP Corepressors To Silence Notch Target Genes

Notch is a transmembrane receptor that determines cell fates and pattern formation in all animal species. After ligand binding, proteolytic cleavage steps occur and the intracellular part of Notch translocates to the nucleus, where it targets the DNA-binding protein RBP-Jκ/CBF1. In the absence of No...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Oswald, Franz, Winkler, Michael, Cao, Ying, Astrahantseff, Kathy, Bourteele, Soizic, Knöchel, Walter, Borggrefe, Tilman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2005
Pynciau:
Gene Expression
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291242/
https://ncbi.nlm.nih.gov/pubmed/16287852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10379-10390.2005
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